depends on where your hairloss is, and what bonding method you want to use. If you use a tape perimeter, and you don't have hairloss at the perimiter then, you can use topicals. But, with everyone you will have to either tape the front hairline or glue it down. You will not be able to use topicals up front unless you get a skin piece and use something like a Got2Be glued attachment that you can release almost at will and reattach. Also, wearing hair has the risk of suffocating your follicles and making your real hairloss worse, but we are all going down the bald path if we are wearing hair. Topicals and a hairpiece is really not that possible unless you want to attach and reattach for every topical application or have a crappy bond that doesn't glule down the topical areas.