I`m sure if any such `damage`ever happened, the manufacturers would have been sued and in any case, such products would have undergone testing to ascertain any possible effects on humans in much the same way that drugs are tested before being allowed for human consumption. I have never heard of any cases of a person suffering any injury from tapes/ glues. Some people may develop a sensitivity / redness of the skin if a particular product didn`t ``agree`` with them ---simply try a different one -- any irritation will be temporary. I would again assert my belief that cleanliness is the key to avoiding problems for long -term wearers --avoid leaving your system attached for long periods, as oils / perspiration building up between the skin and the glue or tape, will lead to skin redness/irritations and probably eventually infection --- common sense has to prevail. I don`t do full -perimeter bonds normally, and even if / when I do, I don`t leave it attached for weeks at a time --- I like to take the system off nightly, gently removing the residue from the scalp, and allowing the skin to breath normally overnight --this is not practical for everybody, but in my experience, prolonged attachments are the cause of issues and not the actual products themselves -- I reckon no matter how gentle a product is, if you leave it on for long periods, the skin can`t breath normally..